Stoke Therapeutics
Massachusetts, United States
26 days ago
Job Type
Min Experience
Over 10 Years
Min Education
Required Travel
Job Function


About Stoke:

Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to addressing the underlying cause of severe diseases. The company is pursuing an entirely new approach to treating severe diseases. We are initially focused on diseases of the central nervous system and the eye, with an emphasis on haploinsufficiencies, which are diseases caused by a loss of about half of the normal protein levels.  Rather than replace, repair or edit faulty genes, we aim to increase – or stoke – protein output from healthy genes to restore functional protein levels using our proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) platform. In all, Stoke has identified ~6500 genes with a TANGO signature, representing broad potential for our approach to help people with severe diseases. 


We recently announced landmark data that support the potential for STK-001 to be the first disease-modifying medicine for Dravet syndrome, a severe and progressive genetic epilepsy that is characterized by frequent, prolonged and refractory seizures, beginning within the first year of life.  The disease is classified as a developmental and epileptic encephalopathy due to the developmental delays and cognitive impairment associated with the disease.


Stoke is also advancing STK-002, a potential treatment for autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. Currently there are no approved treatments for ADOA. Clinical studies of STK-002 are anticipated to start in 2024. The company is pursuing potential new medicines for three additional neurodevelopmental disorders, including Syngap1 and Rett syndrome, in collaboration with Acadia Pharmaceuticals.                                                                                                                                                                                            

Position Purpose:

The VP, Marketing, will lead development of pre-commercial marketing activities, including a potential disease awareness campaign and efforts to enhance genetic testing in Dravet Syndrome. The incumbent will also be responsible for developing a launch strategy and tactics for our lead asset, STK-001 in Dravet Syndrome.  This position will report to the Chief Commercial Officer.

Key Responsibilities:

  • Develop and manage impactful brand and marketing communications. programs, which support key initiatives and market development efforts.
  • Plan and implement campaigns which integrate all appropriate marketing tactics, including digital, interactive and online media, mobile applications, and other new methods that augment traditional marketing tactics.
  • Identify and turn physician/brand insights into actionable programs that have a beneficial impact on the growth of the business.
  • Support key business functions across the business (e.g. DTC campaign, patient access programs, speaker bureau etc.).
  • Creates the execution of a Global Marketing Strategy as well as action plans for sales force aligned activities.
  • Proactively collaborate and strategize with Commercial teams to ensure alignment and develop regionally relevant, robust marketing and promotional programs.
  • Develop STK-001 positioning, messaging platform and corporate brand architecture.
  • Oversee and manage creative agencies. Manage and approve expenditures within budget guidelines.
  • Communicate brand and marketing strategy to the organization, ensuring consistency across all customer touch points. Daily interactions and frequent presentations with the Executive Committee, as well as Board Members.
  • Scope and incorporate appropriate voice of customer research and insights into campaign development and decision-making process.
  • Develop and champion Stoke’s brand to ensure it is consistently and meaningfully represented by all internal stakeholders, across all customer touch points.
  • Develop and/or evolve department operational procedures and processes that foster effective communications.
  • Establish metrics and track program effectiveness and ROI.

Culture & Values:

At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.

Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging Committee (DIB) underscores the importance of DIB to who we are and what we do. 


Stoke operates sites in Bedford, MA, and Cambridge, MA.  This position is a remote position. 


This position will require approximately 50% travel. 

Benefits & Compensation:

At Stoke Therapeutics we are proud to offer comprehensive and competitive employee benefits, including medical, dental and vision insurance; life, long and short-term disability insurance; Paid Parental Leave; a 401K program with company match, unlimited vacation time, and an Employee Stock Purchase Program (ESPP). Compensation is market competitive for the industry and directly commensurate with experience. All positions are bonus and stock eligible.

Interested candidates: Please visit Stoke’s website to learn more and apply directly to the position listed on our Career Center: 

For more information, visit or follow the company on Twitter at @StokeTx.

All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status.

Stoke participates in E-Verify.


Required Skills & Experience:

  • Bachelor's degree required. Master’s degree preferred.
  • Minimum of 15 years of experience required, with 5+ years of marketing executive experience in the pharmaceutical, biotech, life science, medical device or general healthcare industries.
  • Solid acumen around all functions that are integral to successfully evaluating potential opportunities (R&D, regulatory, commercial, financial, manufacturing, legal, etc.).
  • Experience with rare disease product launch.
  • Proven experience managing complex marketing operations processes (Promotional Material Review, Brand Planning, Market Research, CRM Management etc.).
  • Familiarity with marketing automation principles and marketing automation platforms.
  • Strong understanding of related aspects of marketing concepts and principles; patient and consumer marketing.
  • Possess the ability and desire to measure and track performance and success of programs/initiatives.
  • Excellent interpersonal relationship skills including negotiating and relationship management skills with ability to drive achievement of objectives.
  • Ability to manage competing priorities in a fast-paced environment.
  • Experience in managing external agencies and vendors and managing budgets.
  • Proven successful project management skills; strict attention to detail.
  • Drive and enthusiasm for operational improvements.
  • Ability to work in an ambiguous environment and successful track record in building brand teams from the ground up.
  • Excellent communication and people skills.
  • Successful experience in a fast-paced entrepreneurial environment.
  • Marketing and management experience at the VP level
  • Strength in managing people leaders.
Job ID: 73970550
Bedford , Massachusetts , United States
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Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to addressing the underlying cause of severe diseases by up-regulating protein expression with RNA-based medicines. Using the company’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach Stoke is developing antisense oligonucleotides (ASOs) to selectively restore protein levels. The company’s first compound, STK-001 is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. Dravet syndro...

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